acr 368 | BTCC Knowledge

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What is acr-368?

ACR-368 is a potent, selective inhibitor of CHK1 and CHK2 which has shown deep durable single agent activity, including complete responses, in a proportion of patients across several Phase 2 studies of platinum-resistant ovarian cancer and in squamous cell cancers, including anal cancer for which FDA has granted orphan drug designation.

Is acr-368 a good anti-tumor drug?

Currently in phase 2 clinical development, ACR-368 has demonstrated deep, durable single agent anti-tumor clinical activity, including complete responses, in a proportion of patients and a generally favorable safety and tolerability profile across multiple high unmet need solid cancer types.

Is acr-368 effective against ovarian cancer?

ACR-368 has demonstrated deep, durable single-agent anti-tumor clinical activity, including complete responses, in a proportion of patients with platinum-resistant ovarian cancer* and squamous cell cancer ‡.

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